From toxicology to neuroscience, the RccHan®:WIST Rat can play an important role in many studies
The RccHan®:WIST model features a number of attractive intrinsic factors such as lower body weight, enhanced survival rates, and overall lower tumor burden relative to several other strains (e.g., CRL:CD®). In addition, scientists have millions of historical control data points at their disposal for this strain.
These positive attributes can help enhance the 3Rs, improve study outcomes and reduce in-life study costs.
Our new white paper, The RccHan®:WIST Rat: Supporting Advances in Science and Medicine, One Study at a Time, provides a summary of eight recent studies that leveraged this model to advance research.
Download today and understand how this model supported the following eight studies:
- Potential obesity treatment with monoclonal antibodies
- Two-year carcinogenicity study of in utero exposure to acrylamide
- Efficacy of intranasal delivery of levofloxacin
- Assessment of the ability of an investigational pulmonary vasodilator prodrug of treprostinil in development for pulmonary arterial hypertension
- Development of an innovative diet-induced obesity model
- In utero exposure study re: maternal nicotine
- Biologic effects of exogenously administered neurotropic factors on stimulus-evoked release of dopamine
- Effects of monoamine stabilizer compound in regulating impulsive behavior
