Learn how our surgical expertise creates a reliable research model.
The transverse aortic constriction (TAC) rodent model is considered a highly reproducible model of cardiac hypertrophy, a condition that leads to the development of heart failure.
To help researchers understand the inner workings of this delicate microsurgery, we’ve created an informative video of the procedure, which results in a low rate of post-surgery complications and minimal standard deviations in ejection fraction (EF) across cohorts.
Validated internally and externally by scientists and customers, this model displays signs of overt heart failure at just 14 weeks post-surgery.
Understand how the TAC surgery creates a reliable model by watching our one-minute video.
Inotiv excels in performing rodent surgery and in running full disease pharmacology and toxicology studies. Please complete the form to view our video and check the box to request a consultation about our services
