Presented at SOT 2023
Genotoxicity testing is an essential part of hazard and safety evaluation of chemicals and pharmaceuticals. Although two-dimensional (2D) cell culture has been routinely used for genotoxicity testing, it generally lacks the in vivo-like morphological and physiological characteristics and could lead to misleading and non-predictive information of an in vivo response. In the last decade, the three-dimensional (3D) cell culture models have been tested as a novel preclinical test system for safety assessment.
Download your copy to:
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Learn how the 3D Spheroid model can be used as an alternate to standard in vitro MN cell lines
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Review the data to compare the 3D Spheroid model results to the results of the standard 2D model
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Learn the benefits of the 3D Spheroid model vs the standard 2D model
