Athymic nude rats have historically been used for research into tumour biology, immunology and xenograft research. More recently they have been used in toxicology studies, where test article administration to immune-competent animals would result in an inappropriate immune response.
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"Spontaneous Pathology of the Athymic Nude Rat"
by Rowles, A, Bell, D, Liu, KC, Taylor, I, Larsen, JM, Rasmussen, CE and Mowat, V.
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22nd January 2013, 3pm (UK)