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A recorded session from our multi‑presentation genetic toxicology workshop.

This recorded workshop session features Dr. Christopher Sproul presenting practical guidance on the Pig-a gene mutation assay and Duplex Sequencing. This session provides clear, data driven instructions on:

  • Pig-a vs. TGR assay selection.

  • Study design considerations, including dose selection and bone marrow exposure.

  • Interpretation criteria for positive, negative, and equivocal results.

  • Real world data from ENU, 4NQO, B[a]P, and nitrosamine studies.

  • How Duplex Sequencing enables mutation frequency and spectrum analysis. 

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