Working with inbred mice requires monitoring and maintaining genetic variation. To decrease the risks associated with genetic contamination and genetic drift, it is helpful to employ strategic approaches in colony maintenance and make careful considerations when comparing results generated from different substrains of mice.
Increase your awareness and ensure reliable and reproducible experimental data in your mouse colonies. Read our comprehensive overview on this topic and learn more about the C57BL/6 mice and some genetic and phenotypic differences that have arisen across its substrains.
Download today and understand:
- Pathways that lead to genetic variation
- Common genetic and phenotypic differences across certain substrains
- Strategies to help reduce genetic variation in inbred colonies
