This scientific poster presents a comprehensive analysis of proteomic alterations in a rat model of acute kidney injury (AKI) induced by renal ischemia-reperfusion. Using global proteomics and gene expression profiling, the study characterizes protein networks associated with kidney injury and inflammation, highlighting key pathways involved in AKI progression. The findings identify distinct biomarkers and potential therapeutic targets, advancing our understanding of molecular changes underlying renal injury and aiding in the development of targeted AKI therapies.
By exploring this scientific poster, you will:
- Discover how global proteomic profiling reveals significant molecular alterations over time, identifying key pathways such as complement activation, coagulation, and cell adhesion.
- Learn about specific biomarkers like KIM-1 and NGAL, which are temporally upregulated, offering insights into potential therapeutic and diagnostic targets for AKI.
- See how proteomics, gene expression, and immunohistochemistry data combine to provide a robust picture of AKI’s impact on protein networks and biological pathways.
Click here to download this scientific poster!
